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Chromosome analysis provides important information for initial diagnosis and often for the prognosis of hematologic malignancy, monitoring of disease, or the response to therapy. Cytogenetic analysis allows for the identification of acquired abnormalities such as the chromosome rearrangements observed with many types of hematological disorders and constitutional abnormalities such as those associated with certain birth defects.
Peripheral blood, bone marrow, tumor biopsies, and lymph node samples are commonly submitted for chromosome analysis. Chromosome analysis requires the culture of viable cells to produce metaphase chromosome spreads.
The staff of the Cytogenetics Laboratory has extensive experience and expertise in all aspects of chromosome studies including high resolution prenatal and postnatal constitutional analysis, and expert analysis of acquired changes associated with hematologic and other cancers and state-of-the-art fluorescence in situ hybridization (FISH) analyses.
The entire laboratory operates under national technical and medical quality protocols, designed to assure that our tests are performed in accordance with the highest medical and laboratory standards. All cytogenetic testing procedures are performed by certified cytogenetic technologists and supervised by board-certified pathologists and doctoral level scientists
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